THBD Antibody is a Rabbit Polyclonal antibody against THBD. The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.
Target |
THBD |
Reactivity |
Human, Mouse, Rat |
Host |
Rabbit |
Clonality |
Polyclonal |
Tested Applications |
WB |
Recommended dilutions |
WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Recombinant protein of human THBD. |
Purification |
Affinity purified. |
Form |
Liquid |
Isotype |
IgG |
Conjugation |
Unconjugated |
Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Molecular Weight |
Calculated MW: 60 kDa Observed MW: 110 kDa |
Swiss Prot |
P07204
|
GeneID |
7056
|
Gene Symbol |
THBD |
Concentration |
> 1 mg/ml |
Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |