Tacrolimus (FK-506) Antibody is a Mouse monoclonal antibody against FK-506.

Target	FK-506
Reactivity	General (All species)
Host	Mouse
Clonality	Monoclonal
Tested Applications	ELISA
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Immunogen	FK-506 conjugated to BSA.
Purification	Purified from culture by euglobulin precipitation and dialysis.
Form	Liquid
Isotype	IgM
Conjugation	Unconjugated
Specificity	Detects FK-506, a macrolide with similar but more potent immunosuppressant activity than cyclosporine. It is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis. FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogenic organ transplantation to reduce organ rejection.
Storage	Short term: Store at 2-8°C. Long term: Store at -20°C. Prepare working dilutions only prior to immediate use. Avoid repeated freeze/thaw cycles.
Concentration	1.0 mg/ml
Buffer	Tris-buffered saline, pH 8.0, 0.09% NaN3.
UNSPSC Code	12352203
Directions for use	Centrifuge before opening to ensure complete recovery of vial contents.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.