CD3 is a component of T cell surface receptor (TCR), it cantains 5 invariable chains: gamma, delta, epsilon-, and zeta/eta. Clevers et al. (1988) showed the TCR/CD3 complex consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits, CD3 is responsible for the signal transduction of the TCR.
| Target |
CD3 |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
ELISA, FCM |
| Recommended dilutions |
ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Purified recombinant fragment of human CD3 expressed in E. Coli. |
| Purification |
Unpurified Ascites. |
| Isotype |
IgG2a |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
23 kDa |
| Swiss Prot |
P07766
|
| GeneID |
919
|
| Gene Symbol |
CD3E |
| OMIM |
186780
|
| HGNC |
1674 |
| Ensembl |
ENSG00000198851 |
| Buffer |
Ascitic fluid containing 0.03% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |