TBX5 Antibody is a Rabbit Polyclonal antibody against TBX5. This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.
| Target |
TBX5 |
| Reactivity |
Human |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IHC |
| Recommended dilutions |
WB: 1/500 - 1/1000, IHC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant protein of human TBX5. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at 2°C to 8°C upon receipt. |
| Molecular Weight |
Calculated MW: 39 kDa/52 kDa/57 kDa
Observed MW: 61 kDa |
| Swiss Prot |
Q99593
|
| GeneID |
6910
|
| Gene Symbol |
TBX5 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |