Phospho-ZAP-70 (Tyr319) Antibody detects endogenous levels of ZAP-70 only when phosphorylated at Tyrosine 319. ZAP70 (human) a tyrosine kinase of the Syk family. Associates with the T-cell antigen receptor zeta-chain after TCR stimulation. Phosphorylated by Src-family kinases following antigen receptor activation. Plays a role in lymphocyte activation.
| Target |
ZAP-70 (pY319) |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Purification |
Purified by affinity chromatography. |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
P43403
|
| GeneID |
7535
|
| Gene Symbol |
ZAP70 |
| OMIM |
176947
|
| Enzyme Commission Number |
EC 2.7.10.2 |
| HGNC |
12858 |
| Ensembl |
ENSG00000115085 |
| Buffer |
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |