产品名称 X-Ray Repair Cross Complementing 5 (XRCC5) Antibody
产品货号 Catalogue No: abx026529
产品价格 现货询价,电话:010-67529703
产品规格 Available Options * Size: 80 µl 400 µl
产品品牌 abbexa
产品概述
产品详情
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V (D) J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V (D) J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Target XRCC5
Reactivity Human
Host Rabbit
Clonality Polyclonal
Tested Applications WB, IF/ICC, FCM
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Immunogen KLH-conjugated synthetic peptide between 424-450 amino acids from the Central region of human XRCC5.
Purification Purified through a protein A column, followed by peptide affinity purification.
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot P13010
NCBI Accession NP_066964.1
Buffer PBS containing 0.09% sodium azide.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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