Phospho-Vinculin (Tyr821) Antibody detects endogenous levels of Vinculin only when phosphorylated at Tyrosine 821. Vinculin binding sites have been identified on other cytoskeletal proteins, including Talin and alpha actinin. In addition, vinculin, Talin and alpha actinin each contain Actin binding sites. Expression of vinculin and Talin has been shown to be affected by the level of Actin expression.
| Target |
Vinculin (pY821) |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Purification |
Purified by affinity chromatography. |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
P18206
|
| GeneID |
7414
|
| Gene Symbol |
VCL |
| OMIM |
193065
|
| HGNC |
12665 |
| Ensembl |
ENSG00000035403 |
| Buffer |
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |