UBE2C Antibody is a Rabbit Polyclonal antibody against UBE2C. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.

Target	UBE2C
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Tested Applications	WB, IHC, IF/ICC, IP
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/100, IP: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Recombinant protein of human UBE2C.
Purification	Affinity purified.
Form	Liquid
Isotype	IgG
Conjugation	Unconjugated
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight	Calculated MW: 15 kDa/16 kDa/17 kDa/19 kDa Observed MW: 17 kDa
Swiss Prot	O00762
GeneID	11065
Gene Symbol	UBE2C
Concentration	> 1 mg/ml
Buffer	PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
UNSPSC Code	12352203
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.