Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.
Target |
UCH37 |
Reactivity |
Human |
Host |
Mouse |
Clonality |
Monoclonal |
Tested Applications |
WB |
Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Purified His-tagged UCH37 protein |
Purification |
Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
Isotype |
IgG1 |
Conjugation |
Unconjugated |
Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Swiss Prot |
Q9Y5K5
|
NCBI Accession |
NP_001186190.1
NP_001186191.1
NP_001186192.1
NP_057068.1
|
Buffer |
PBS containing 0.09% sodium azide. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |