This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways.It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon.Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
| Target |
JAK2 |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
ELISA, WB |
| Recommended dilutions |
ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Purified recombinant fragment of JAK2 (745-955aa) expressed in E. coli. |
| Purification |
Unpurified Ascites. |
| Isotype |
IgG1 |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
130.6 kDa |
| Swiss Prot |
O60674
|
| GeneID |
3717
|
| Gene Symbol |
JAK2 |
| OMIM |
147796
|
| HGNC |
6192 |
| Ensembl |
ENSG00000096968 |
| Buffer |
Ascitic fluid containing 0.03% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |