T protein p53 binding protein 1 may have a role in checkpoint signaling during mitosis,enhance TP53-mediated transcriptional activation and play a role in the response to DNA damage.
| Target |
TP53BP1 |
| Reactivity |
Human |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
ELISA, WB, IHC, FCM |
| Recommended dilutions |
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Purified recombinant fragment of human TP53BP1 (AA: 574-773) expressed in E. coli. |
| Purification |
Purified antibody |
| Isotype |
IgG1 |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
213.6 kDa |
| Swiss Prot |
Q12888
|
| GeneID |
7158
|
| Gene Symbol |
TP53BP1 |
| OMIM |
605230
|
| HGNC |
11999 |
| Ensembl |
ENSG00000067369 |
| Concentration |
1.0 mg/ml |
| Buffer |
PBS with 0.05% sodium azide and 0.5% protein stabilizer. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |