TRPV6 Antibody is a Rabbit Polyclonal antibody against TRPV6. The transient receptor potential (TRP) protein family consists of a diverse group of cation channels functioning in a variety of homeostatic and regulatory pathways. Four subfamilies exist, based on channel domain homology, not activating stimuli: C type (canonical or classical), V type (vanilloid receptor related), M type (melastatin related) and P type (PKD). TRPV6 belongs to the V type subfamily, and it facilitates calcium entry across the plasma membrane in pancreas, placenta, and to a lesser extent stomach and kidney tissue. Furthermore, prostate cancer cells overexpress TRPV6, while benign prostate tissues do not express the protein, implying a role for TRPV6 in malignant growth.
| Target |
TRPV6 |
| Reactivity |
Human |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant fusion protein of human TRPV6. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at 2°C to 8°C upon receipt. |
| Molecular Weight |
Calculated MW: 68 kDa/87 kDa
Observed MW: 70 kDa |
| Swiss Prot |
Q9H1D0
|
| GeneID |
55503
|
| Gene Symbol |
TRPV6 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |