This locus encodes the transforming growth factor (TGF)-beta type III receptor.The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members.Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling.Decreased expression of this receptor has been observed in various cancers.Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
| Target |
TGFBR3 |
| Reactivity |
Human, Mouse |
| Host |
Mouse |
| Clonality |
Monoclonal |
| Tested Applications |
ELISA, WB |
| Recommended dilutions |
ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Purified recombinant fragment of human TGFBR3 (AA: 147-328) expressed in E. coli. |
| Purification |
Purified antibody |
| Isotype |
IgG1 |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
93.4 kDa |
| GeneID |
7049
|
| Concentration |
1.0 mg/ml |
| Buffer |
PBS with 0.05% sodium azide and 0.5% protein stabilizer. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |