TIMP1 Antibody detects endogenous levels of total TIMP1. TIMP1 Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16.
| Target |
TIMP1 |
| Reactivity |
Human, Mouse, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB |
| Recommended dilutions |
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Synthesised peptide derived from human TIMP1 |
| Purification |
Purified by immunogen affinity chromatography. |
| Form |
Liquid |
| Conjugation |
Unconjugated |
| Specificity |
TIMP1 Antibody detects endogenous levels of total TIMP1 |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
24 kDa |
| Swiss Prot |
P01033
|
| Gene Symbol |
TIMP1 |
| Ensembl |
ENSG00000102265 |
| Concentration |
1 mg/ml |
| Buffer |
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |