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Antigenic Specificity | Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB),ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MANF is a trophic factor for midbrain dopamine neuronsin vivo. It prevents the 6-OHDA-induced degeneration of dopamine neurons in rodent models of Parkinson'sdisease (Lindholm et al., 2008, Voutilainen et al., 2009). When administeredafter 6-OHDA-lesioning it restores the dopaminergic function and prevents degenerationof dopamine neurons in substantia nigra pars compacta |
Immunogen | Recombinant human MANF protein produced using CHO-basedIcosagen Cell factory Ltd. proprietary suspension cell line. Immunogen is purifiedfrom cell culture supernatant |
Other Names | MANF|ARMET|ARP-like|CG7013|DmMANF|Dmel\\CG7013|anon-EST:ParkEST188|arp|armet|im:6909481|zgc:153327|ARP|3230402M22Rik|AA407711|AA408789|AA673178|Armet|D17914|D18Mgi17|RBM15B |
Gene, Accession # | Gene ID: 7873 |
Catalog # | ABIN956417 |
Price | |
Order / More Info | Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |