| 产品详情 |
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| Product Name | Fevipiprant |
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| Description | Purity >98% by HPLC. Fevipiprant is a prostaglandin D2 (PGD2) receptor antagonist with a Kd value of 1.14 nM for CRTH2/DP2. It has been shown to inhibit PGD2-stimulated human eosinophil shape change in whole blood assays (IC50 = 0.44 nM) and to inhibit PGD2-induced cytokine release in human Th2 cells (IC50s = 2.56 and 1.4 nM for IL-5 and IL-13, respectively). This compound has undergone testing in a phase II clinical study in uncontrolled allergic asthma. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-(2-methyl-1-(4-(methylsulfonyl)-2-(trifluoromethyl)benzyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid, NVP-QAW039, QAW039 |
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| Gene, Accession, CAS # | CAS: 872365-14-5 |
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| Catalog # | LS-H4126 |
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| Order / More Info | Fevipiprant from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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