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Product Name | Recombinant Human Serine protease HTRA1 |
Description | 23-480aa; Full Length. MW: 65.02kD. Purity >90% as determined by SDS-PAGE. Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signa |
Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
Concentration | n/a |
Applications | n/a |
Other Names | [High-temperature requirement A serine peptidase 1; L56; Serine protease 11] |
Gene, Accession, CAS # | HTRA1, Gene ID: 5654, Accession: NP_002766.1 |
Catalog # | MBS1445137 |
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Order / More Info | Recombinant Human Serine protease HTRA1 from MYBIOSOURCE INC. |
Product Specific References | Primary structure of a putative serine protease specific for IGF-binding proteins.Zumbrunn J., Trueb B.FEBS Lett. 398:187-192(1996) |
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