| 产品详情 |
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| Antigenic Specificity | CD80 |
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| Clone | RM80 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a |
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| Format | Protein G purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | Flo (1:10 - 1:50), IHC, IHC-Fr |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD80 Antibody (clone RM80) LS-C44886. Recognizes mouse CD80 (B7-1), a 60kD cell surface glycoprotein which is a member of the CD28/B7 family. In mice, CD80 is expressed on monocytes, peritoneal macrophages and dendritic cells, and expression may be significantly increased upon B lymphocytes by LPS and by IL-4. CD80 has been identified as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4), two structurally similar molecules expressed on T cells. CD28 and CTLA4 are two receptors that have essential but opposing functions in T-cell stimulation. The Interaction of CD80 with CD28 stimulates and sustains T cell responses, whereas the interaction of CD80 with CTLA4 is reported to inhibit T-cell responses. |
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| Immunogen | BCL1 cells expressing CD80. |
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| Other Names | CD80, Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CD80 antigen, LAB7, CD80 molecule, CTLA-4 counter-receptor B7.1 |
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| Gene, Accession # | CD80, Gene ID: 941 |
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| Catalog # | LS-C44886 |
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| Price | |
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| Order / More Info | CD80 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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