| 产品详情 |
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| Product Name | AK-7 |
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| Description | Purity >98% by NMR, TLC. AK-7 is a selective Sirt2 inhibitor (IC50=15.5 uM) which does not inhibit Sirt1 or Sirt3. It down regulates cholesterol biosynthesis genes in primary striatal neurons. AK-7 displays neuroprotective effects in Huntington's disease mouse models including improved motor function, extended survival and reduced brain atrophy all of which were associated with reduced aggregated mutant huntingtin. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-(1-Azepanylsulfonyl)-N-(3-bromophenyl)benzamide |
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| Gene, Accession, CAS # | CAS: 420831-40-9 |
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| Catalog # | LS-H14590 |
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| Price | |
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| Order / More Info | AK-7 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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