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| Product Name | NuDT1, 1-156aa, Human, His tag, E Coli |
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| Description | MW: 20.1kDa (176aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. NuDT1 is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. It is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and m |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1mg/ml (determined by BCA) |
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| Applications | SDS-PAGE |
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| Other Names | [78-dihydro-8-oxoguanine triphosphatase; MTH1; 8-oxo-dGTPase; Nudix motif 1; 7,8-dihydro-8-oxoguanine triphosphatase] |
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| Gene, Accession, CAS # | NuDT1, Gene ID: 4521, Accession: NP_945191 |
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| Catalog # | MBS203533 |
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| Order / More Info | NuDT1, 1-156aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Satoh J., et al (2000) Eur J Neurol. 7 (6):673-7.; Oda H., et al. (1997) J. Biol. Chem. 272:17843-17850; |
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