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| Product Name | Recombinant Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) Viral interleukin-10 homolog |
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| Description | 20-175aa; Full Length. MW: 34kD. Purity >90% as determined by SDS-PAGE. Functional viral IL-10 homolog. Can bind to the human IL-10 receptor and compete with human IL-10 for binding sites. Requires both subunits of the human IL-10 receptor complex to induce signal transduction events and biological activities. IL-10 signaling pathway has several immunosuppressive activities that are exploited by the virus. Inhibits TLR-induced type I interferon production in host plasmacytoid dendritic cells. |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.05 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [cmvIL-10; vIL-10] |
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| Gene, Accession, CAS # | UL111A, Accession: P17150.2 |
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| Catalog # | MBS1207943 |
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| Order / More Info | Recombinant Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) Viral interleukin-10 homolog from MYBIOSOURCE INC. |
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| Product Specific References | Human cytomegalovirus-encoded interleukin-10 homolog inhibits maturation of dendritic cells and alters their functionality.Chang W.L., Baumgarth N., Yu D., Barry P.A.J. Virol. 78:8720-8731(2004) |
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