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| Product Name | Recombinant Human Probable ATP-dependent RNA helicase DDX58 |
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| Description | 1-430aa; Partial. MW: 53.3kD. Purity >90% as determined by SDS-PAGE. Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons and proinflammatory cytokines. Its ligands include: 5'-triphosphorylated ssRNA and dsRNA and short dsRNA (<1 kb in length). In addition to the 5'-triphosphate moiety, blunt-end base pairing at |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [DEAD box protein 58; RIG-I-like receptor 1; RLR-1; Retinoic acid-inducible gene 1 protein; RIG-1; Retinoic acid-inducible gene I protein; RIG-I] |
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| Gene, Accession, CAS # | DDX58, Gene ID: 23586, Accession: NP_055129.2 |
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| Catalog # | MBS1040007 |
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| Order / More Info | Recombinant Human Probable ATP-dependent RNA helicase DDX58 from MYBIOSOURCE INC. |
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| Product Specific References | RIG-I, a human homolog gene of RNA helicase, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell.Sun Y.-W.Thesis (1997), Shanghai Institute of Hematology, ChinaRetinoic acid-inducible gene-I is induced in endothelial cells by LPS and regulates expression of COX-2.Imaizumi T., Aratani S., Nakajima T., Carlson M., Matsumiya T., Tanji K., Ookawa K., Yoshida H., Tsuchida S., McIntyre T.M., Prescott S.M., Zimmerman G.A., Satoh K.Biochem. Biophys. Res. Commun. 2 |
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