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| Product Name | Recombinant Human cytomegalovirus Viral interleukin-10 homolog (UL111A) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 34kDa. Full Length of Mature Protein: 20-175aa. N-terminal 6xHis-SUMO-tagged. Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5). Functional viral IL-10 homolog. Can bind to the human IL-10 receptor and compete with human IL-10 for binding sites. Requires both subunits of the human IL-10 receptor complex to induce signal transduction events and biological activities. IL-10 signaling pathway has several immunosuppressive activities that are exploited by the virus. Inhibits TLR-induced type I interferon production in host plasmacytoid dendritic cells. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | cmvIL-10; vIL-10 |
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| Gene, Accession, CAS # | UL111A, UniProt: P17150 |
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| Catalog # | RPC22459 |
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| Order / More Info | Recombinant Human cytomegalovirus Viral interleukin-10 homolog (UL111A) from BIOMATIK |
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| Product Specific References | n/a |
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