| 产品详情 |
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| Antigenic Specificity | TLR4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat, bovine |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB, IHC-P, IF(IHC-P), IF(ICC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TLR4 Polyclonal Antibody. • Target Background: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, |
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| Immunogen | KLH conjugated synthetic peptide derived from rat TLR4. Immunogen Range: 780-830/835 |
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| Other Names | Lps; Ly87; Ran/M1; Rasl2-8; Toll-like receptor 4; CD284; Tlr4 |
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| Gene, Accession # | Gene ID: 21898, SwissProt: Q9QX05 |
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| Catalog # | bs-1021R |
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| Price | |
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| Order / More Info | TLR4 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Yang, J. et al. (2013) J Ethnopharmacol. PubMed: 24432369 // Tang, L. et al. (2011) Arch Oral Biol.56(10):1064-72. PubMed: 21457942 // Chen, X. et al. (2014) Carbohydr Polym. PubMed: 24708959 // Xing, Shanshan, et al. (2014) J Int Med Res. PubMed: 24925583 // Wang, Dunjing, et al. (2015) Inflammation. PubMed: 26002587 // Namisaki, Tadashi, et al. (2015) J Gastroenterol. PubMed: 26190501 // Arfian, Nur, et al. (2016) Kobe J. Med. Sci 62.2. PubMed: 27578035 // Kawakita, Fumihiro, et al.(2016) Mol Neurobiol. PubMed: 27738873 // Harasymowicz, Natalia S., et al. (2017) Arthritis Rheumatol. PubMed: 28320058 // Jenvey, Caitlin J. et al. (2017) J Hist Histopath. // Kulhankova, Katarina, et al. (2017) Infect Immun. PubMed: 29229737 // Xu, Wei, et al. (2017) Cell Physiol Biochem. PubMed: 29241205 // Wang et al. (2016) Mol.Med.Rep. 13:4289-302. PubMed: 27035565 // Qiao et al. (2015) Int.J.Clin.Exp.Med. 8:4016-23. PubMed: 26064304 // Zhao et al. (2016) Mediators.Inflamm. 2016:4706915. PubMed: 27478307 // Arfian et al. (2016) Kobe.J.Med.Sci. 62:E38-44. PubMed: 27578035 |
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