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| Product Name | Naringenin |
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| Description | Purity >98%. Naringenin is a citrus-derived flavonoid that inhibits CYP3A4 activity in human liver microsomes (IC50 s = 139-188 µM). At 100 mg/kg/day, naringenin selectively inhibits the transcription of Smad3 and directly down-regulates TGF-Beta1, significantly reducing lung metastasis in mice with bleomycin-induced pulmonary fibrosis. Naringenin demonstrates both lipid lowering and insulin-like properties in low-density lipoprotein (LDL) receptor-deficient mice fed a Western diet containing 1-3% naringenin by correcting VLDL overproduction, ameliorating hepatic steatosis, and attenuating dyslipidemia without affecting caloric intake or fat absorption. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, NSC 11855, NSC 34875, Salipurol, S-Dihydrogenistein |
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| Gene, Accession, CAS # | CAS: 67604-48-2 |
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| Catalog # | LS-H8916 |
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| Order / More Info | Naringenin from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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