| 产品详情 |
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| Product Name | Naringin |
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| Description | Purity >95%. Naringenin is a citrus-derived flavonoid that inhibits cytochrome P450 (CYP) 3A4 activity in human liver microsomes (IC50 s = 139-188 µM). Naringin is a natural flavanone glycoside formed from naringenin and neohesperidose. It undergoes extensive metabolism in the liver, giving rise to naringenin and other bioactive metabolites that have anti-oxidant, anti-inflammatory, and anti-apoptotic effects. Naringin is a weak inhibitor of CYP3A4, providing 14% inhibition at 200 µM. It suppresses apoptosis in neurons and increases the expression of neurotrophic factor in dopaminergic neurons, providing neuroprotection. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2S)-7-[[2-O-(6-deoxy-a-L-mannopyranosyl)-Beta-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, NSC 5548 |
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| Gene, Accession, CAS # | CAS: 10236-47-2 |
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| Catalog # | LS-H8918 |
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| Order / More Info | Naringin from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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