| 产品详情 |
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| Product Name | Bepridil (hydrochloride) |
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| Description | Purity >98%. Bepridil is a dihydropyridine that has anti-anginal and anti-arrhythmic actions by blocking calcium channels in heart and smooth muscle. It is recognized as a non-selective channel blocker, altering myocardial Ca2+, Na+, and K+ currents. For example, it blocks voltage-gated Ca2+ (Cav 3.2) and K+ (hERG and KCNQ4) channels, sarcoplasmic ATP-sensitive K+ (KATP ) channels, and Na+ -activated (KNa ) channels (IC50 s = 7.1, 22, 9.4, 10, and 2.2 µM, respectively). It also activates mitochondrial ATP-sensitive KATP channels (ED50 = 27.5 µM). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Beta-[(2-methylpropoxy)methyl]-N-phenyl-N-(phenylmethyl)-1-pyrrolidineethanamine, monohydrochloride |
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| Gene, Accession, CAS # | CAS: 68099-86-5 |
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| Catalog # | LS-H6767 |
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| Price | |
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| Order / More Info | Bepridil (hydrochloride) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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