| 产品详情 |
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| Product Name | Berberine chloride |
| Description | Purity >98% by TLC. Natural fluorescent dye, used in histology for staining heparin in mast cells. An isoquinoline alkaloid, which shows antibacterial, antifungal, anti-inflammatory, anti-oxidant, antidiabetic, antiviral and anticancer activity. It inhibits cell growth and induces apoptosis in a variety of cancer cell lines. Broad spectrum enzyme inhibitor, affects N-acetyltransferase, cyclooxygenase-2, and topoisomerase activities and gene/protein expression. Increases adiponectin expression, upregulates LDLR and insulin receptor. Anti-hyperglycemic, by inhibition of aldose reductase, inducing glycolysis, preventing insulin resistance through increasing insulin receptor expression and acting like incretins. Activates AMPK and ERK. Potent, uncompetitive, reversible IDO 1 inhibitor with IC50 values of 7 µM (cell-based assay) and 9.3 µM (enzymatic assay), and Ki value 8µM. |
| Size | n/a |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Natural Yellow 18, Berberinium chloride, BBR, Umbellatine, Majarine, Thalsine |
| Gene, Accession, CAS # | CAS: 633-65-8 |
| Catalog # | LS-H258 |
| Price | |
| Order / More Info | Berberine chloride from LIFESPAN BIOSCIENCES INC. |
| Product Specific References | n/a |
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