| 产品详情 |
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| Antigenic Specificity | GSK3 Alpha/Beta Tyr279+Tyr216 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB, FCM, IHC-P, IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GSK3 Alpha/Beta(Tyr279+Tyr216) Antibody. • Target Background: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Re |
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| Immunogen | KLH conjugated synthetic phosphopeptide derived from human GSK3 Alpha/Beta around the phosphorylation site of Tyr279/Tyr216. Immunogen Range: 250-300/483 |
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| Other Names | Phosphorylated, phospho-Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine/threonine-protein kinase GSK3A; GSK3A |
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| Gene, Accession # | Gene ID: 29312932, SwissProt: P49840 |
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| Catalog # | bs-2073R |
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| Price | |
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| Order / More Info | GSK3 Alpha/Beta Tyr279+Tyr216 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Zhao, H. et al. (2012) Behav Brain Res.241:228-34. PubMed: 23219964 |
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