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| Product Name | PARK2,1-465aa, Human, His tag, E Coli (Denatured) |
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| Description | MW: 53.8 kDa (485aa). Purity >80% by SDS-PAGE. The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [E3 ubiquitin-protein ligase parkin; AR-JP; LPRS2; PDJ; PRKN] |
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| Gene, Accession, CAS # | PARK2, Gene ID: 5071, Accession: NP_004553.2 |
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| Catalog # | MBS205689 |
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| Order / More Info | PARK2,1-465aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | Imai Y., et al. (2000) J. Biol. Chem. 275:35661-35664; Shimura H., et al. (2000) Nat. Genet. 25:302-305; |
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