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| Product Name | Recombinant Human Negative elongation factor B |
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| Description | 8-199aa; Partial. MW: 49.2kD. Purity >90% as determined by SDS-PAGE. Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. May be able to induce chromatin unfolding. |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Cofactor of BR; CA1] |
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| Gene, Accession, CAS # | COBRA1, Gene ID: 25920, Accession: NP_056271.3 |
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| Catalog # | MBS717301 |
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| Price | |
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| Order / More Info | Recombinant Human Negative elongation factor B from MYBIOSOURCE INC. |
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| Product Specific References | BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations.Ye Q., Hu Y.-F., Zhong H., Nye A.C., Belmont A.S., Li R.J. Cell Biol. 155:911-921(2001) Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., Yamamoto J., Saito K., Kawai |
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