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| Product Name | Recombinant Human Angiopoietin-2 (ANGPT2), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 55.7kDa. Partial: 19-485aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | ANGPT2, UniProt: O15123 |
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| Catalog # | RPC24489 |
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| Order / More Info | Recombinant Human Angiopoietin-2 (ANGPT2), partial from BIOMATIK |
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| Product Specific References | n/a |
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