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Product Name | Sequestosome 1 (SQSTM1) (AA 1-356) protein (His tag) |
Description | SQSTM1 is an adapter protein which binds ubiquitin and mediates the activation of NFKB1 by TNF-a, NGF and IL-1. SQSTM1 is involved in titin/TTN downstream signaling in muscle cells. SQSTM1 controls signaling cascades through ubiquitination. SQSTM1 participates in cell differentiation, apoptosis, immune response and regulation of K(+) channels. Mutations in UBA domain of the SQSTM1 protein cause Paget's disease because the UBA is essential for aggregate sequestration and cell survival Synonyms: A170, OSIL, p60, p62, p62B, PDB3, ZIP3, EBIAP, ORCA, OSIL, SQSTM1 |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | SQSTM1|sqstm1|MGC79491|A170|OSIL|PDB3|ZIP3|p60|p62|p62B|OSF-6|Osi|STAP|ZIP|sb:cb621|zgc:85784 |
Gene, Accession, CAS # | Gene ID: 8878 |
Catalog # | ABIN807747 |
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Order / More Info | Sequestosome 1 (SQSTM1) (AA 1-356) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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