| 产品详情 |
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| Antigenic Specificity | CD86 |
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| Clone | monoclonal |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2b |
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| Format | fluorescein (FITC) conjugate |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | Flo |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD86 Antibody (FITC) LS-C44889. Recognizes mouse CD86 (B7-2), an 80kD cell surface glycoprotein which is a member of the CD28/B7 family. In mouse CD86 is expressed at high levels on peripheral blood monocytes and dendritic cells, and at low levels on resting B and T-lymphocytes. Expression of CD86, on these cell populations, can be increased upon activation. CD86 has been identified, along with CD80 (B7-1), as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA4). CD28 and CTLA4 are two receptors that have opposing functions in T-cell stimulation. Interaction of CD86 with CD28 promotes a number of T-cell activities, whereas the binding of CD86 to CTLA4 inhibits T-cell responses. The PO3 antibody has been reported to block some co-stimulatory functions of CD86. XXX recommend the use of MCA2463EL for this purpose. |
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| Immunogen | Mouse B-cell line, BCL1. |
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| Other Names | CD86, Activation B7-2 antigen, B7-2, B7.2, B70, CD86 molecule, CTLA-4 counter-receptor B7.2, CD86 antigen, FUN-1, LAB72, BU63, CD28LG2, Ctla-4 counter-receptors b7.2 |
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| Gene, Accession # | CD86, Gene ID: 942 |
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| Catalog # | LS-C44889 |
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| Price | |
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| Order / More Info | CD86 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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