| 产品详情 |
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| Product Name | NS-304 |
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| Description | Purity >98%. Prostaglandin I2 (PGI2 ) is a potent vasorelaxant and inhibitor of human platelet aggregation that mediates its actions by binding to a specific G protein-coupled receptor, the IP receptor, on the surface of endothelial cells and platelets. The IP receptor also participates in signal transduction of the pain response, cardioprotection, and inflammation. NS-304 is a prodrug of the active form of MRE-269, which is a potent and selective agonist for the human IP receptor with a Ki value of 20 nM. In contrast to prostaglandin I2, which has a half-life of 30 seconds to a few minutes in vivo, NS-304 is long-acting. Plasma concentrations of MRE-269 remain near peak levels for more than eight hours in rats and dogs after NS-304 was administered orally. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[4-[(5,6-diphenylpyrazinyl)(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)-acetamide, ACT-293987, Selexipag |
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| Gene, Accession, CAS # | CAS: 475086-01-2 |
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| Catalog # | LS-H9078 |
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| Price | |
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| Order / More Info | NS-304 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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