| 产品详情 |
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| Product Name | Recombinant Mouse Phospholipase A-2-activating protein (Plaa), partial |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 13.6. Partial: 495-584aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Mus musculus (Mouse). Plays a role in protein ubiquitination, sorting and degradation through its association with VCP. Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. Plays a role in cerebellar Purkinje cell development (PubMed:28413018). Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha- or lipopolysaccharide-dependent manner, and hence prostaglandin E2 biosynthesis. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | PLA2P (PLAP) (Plap) |
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| Gene, Accession, CAS # | Plaa, UniProt: P27612 |
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| Catalog # | RPC26394 |
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| Order / More Info | Recombinant Mouse Phospholipase A-2-activating protein (Plaa), partial from BIOMATIK |
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| Product Specific References | n/a |
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