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Product Name | Human AGO2 Partial protein |
Description | AGO2 is required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by AGO2. MW: 38.1 kDa. Purity >90% as determined by SDS-PAGE. |
Size | 50 ug, 200 ug, 500 ug, 1 mg, 10 ug, 100 ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | AGO2 protein |
Gene, Accession, CAS # | UniProt: Q9UKV8 |
Catalog # | orb244993 |
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Order / More Info | Human AGO2 Partial protein from BIORBYT LTD. |
Product Specific References | n/a |
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