产品名称 Sprouty Homolog 4 (Drosophila) (SPRY4) (aa 306-322) Antibody from ANTIBODIES-ONLINE GmbH
产品货号 ABIN129626
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 ANTIBODIES-ONLINE GmbH
产品概述
产品详情
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Antigenic SpecificitySprouty Homolog 4 (Drosophila) (SPRY4) (aa 306-322)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size100 µg
Concentrationn/a
ApplicationsWestern Blotting (WB),ELISA,Immunohistochemistry (IHC)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionSprouty-4 (also known as SPRY4) is an inhibitor of the insulin receptor and EGFR-transduced mitogen-activated protein kinase (MAPK) signaling pathway downstream of FGF and EGF receptor tyrosine kinase activation. It is positioned upstream of RAS activation and impairs the formation of active GTP-RAS. SPRY4 is widely expressed, with different isoforms. The protein consists of 322 amino acids, with a cysteine-rich region, Src homology 3 binding regions, proline-rich regions, and a PEST sequence. It is expressed predominantly in the cytoplasm. Northern results show bands across most tissues, with strongest expression in heart, brain, placenta, lung, and intestine.Synonyms: Sprouty-4, SPRY4
ImmunogenThis affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 306-322 of Human Sprouty-4 protein.
Other NamesSPRY4|LOC100218545|HH17|A030006O18Rik|sprouty4
Gene, Accession #n/a
Catalog #ABIN129626
Price
Order / More InfoSprouty Homolog 4 (Drosophila) (SPRY4) (aa 306-322) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
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