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| Antigenic Specificity | CELA3B / ELA3B, aa 82-238 |
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| Clone | CELA3B/2809R |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | Protein A/G purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC-Fx, SDS-PAGE |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CELA3B / ELA3B Antibody (aa 82-238, clone CELA3B/2809R) LS-C751140. This MAb recognizes a protein of ~30 kDa , identified as CELA3B (Chymotrypsin like elastase family member 3B). Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein; it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function. |
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| Immunogen | Recombinant human CELA3B protein fragment (around aa 82-238). Antigen Molecular Weight: ~17 kDa |
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| Other Names | CELA3B, CBPP, Elastase 1, ELA3B, Elastase IIIB, Elastase-3B, EL-1, Fecal elastase 1, Pancreatic elastase IIIb, Pancreatic elastase 1, Pancreatic endopeptidase E, Protease E, Elastase 3B, pancreatic, Proteinase E |
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| Gene, Accession # | CELA3B, Gene ID: 23436 |
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| Catalog # | LS-C751140 |
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| Price | |
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| Order / More Info | CELA3B / ELA3B, aa 82-238 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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