| 产品详情 |
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| Antigenic Specificity | LAMP2 |
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| Clone | H4B4 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | Alexa Fluor 488 conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 4 µLx100 µL whole blood or 10^6 cells, Immunocytochemistry: 1:100, Immunofluorescence: 1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LAMP2 Monoclonal Antibody (H4B4), Alexa Fluor 488. CD107b (lysosome-associated membrane protein-2, LAMP-2), together with CD107a / LAMP-1, is a major constituent of lysosomal membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes, especially CD107b is important regulator in successful phagosomal maturation. CD107b deficiency causes an accumulation of autophagosomes in many tissues leading to cardiomyopathy and myopathy (Danons disease). Immature CD107b is an approximately 45 kDa protein, but after extensive glycosylation the mature glycoprotein has about 100-120 kDa. |
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| Immunogen | n/a |
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| Other Names | CD107b, LAMP-2, LAMPB, LGP110, CD107 antigen-like family member B, lysosome-associated membrane glycoprotein 2, lysosome-associated membrane protein 2 |
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| Gene, Accession # | Entrez: 3920; Uniprot: P13473 |
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| Catalog # | MA5-18122 |
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| Price | |
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| Order / More Info | LAMP2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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