产品详情 |
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Antigenic Specificity | CD8a Molecule (CD8A) |
Clone | hCD8 |
Host Species | Mouse |
Reactive Species | sheep |
Isotype | n/a |
Format | biotin conjugate |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 acts as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional CD8 is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 identifies cytotoxic/suppressor t-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of t-cell mediated killing. CD8 alpha chains binds to class-I MHC molecules alpha-3 domainsSynonyms: CD8, MAL, p32 |
Immunogen | n/a |
Other Names | cd8|LOC100136450|BB154331|Ly-2|Ly-35|Ly-B|Lyt-2|zgc:136643|CD8|Leu2|MAL|p32|RHACD8-4 |
Gene, Accession # | Gene ID: 925 |
Catalog # | ABIN808138 |
Price | |
Order / More Info | CD8a Molecule (CD8A) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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