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| Product Name | Ras Homolog Enriched in Brain (RHEB) (AA 1-181) protein (T7 tag) |
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| Description | RHEB is part of the Ras and GTPase superfamily that was originally identified as an immediate-early gene in brain but is also widely expressed in other tissues. RHEB encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. RHEB is necessary in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. RHEB has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. RHEB induces oncogenic transformation. RHEB overexpression accelerates lymphomagenesis and is associated with prostate cancer. RHEB can cytopathologically distinguish between fibroadenoma from malignant breast carcinomas which is considered as a secondary diagnostic tool. RHEB has a central role in the regulation of the Ras/B-Raf/C-Raf/MEK signaling network Synonyms: RHEB2, GTP-binding protein Rheb, MGC111559, Ras homolog enriched in brain, RHEB |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | RHEB|rheb2|im:7161941|zgc:153231|RHEB2 |
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| Gene, Accession, CAS # | Gene ID: 6009 |
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| Catalog # | ABIN806726 |
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| Order / More Info | Ras Homolog Enriched in Brain (RHEB) (AA 1-181) protein (T7 tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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