| 产品详情 |
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| Product Name | Ubiquitously Transcribed Tetratricopeptide Repeat Gene, Y Chromosome (UTY) peptide |
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| Description | Induction of antigen-specific tolerance to transplantation antigens is desirable to control host-versus-graft and graft-versus-host reactions. Intranasal administration of individual major histocompatibility complex (MHC) class II-restricted HY peptides induces indefinite survival of syngeneic male skin grafts and allows engraftment of male bone marrow. Humans make male-specific T-cell responses to HY peptides from the same genes, SMCY, UTY, and DBY, strongly conserved across mammalian species, and from additional ubiquitously transcribed human Y chromosome genes, RPS4Y and DFFRY.Using immature, bone marrow-erived dendritic cells (BMDCs) pulsed with the immunodominant MHC class I (H2Db)-estricted HY peptide, WMHHNMDLI, encoded by the Uty gene, (HYDbUty) to induce tolerance to syngeneic male skin grafts in H2b mice. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN399527 |
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| Order / More Info | Ubiquitously Transcribed Tetratricopeptide Repeat Gene, Y Chromosome (UTY) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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