| 产品详情 |
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| Product Name | Insulin-Degrading Enzyme (IDE) peptide |
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| Description | This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
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| Other Names | zgc:162603|IDE|1300012G03Rik|4833415K22Rik|AA675336|AI507533|INSDEGM|INSULYSIN |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN936344 |
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| Price | |
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| Order / More Info | Insulin-Degrading Enzyme (IDE) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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| 产品资料 |
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