| 产品详情 |
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| Antigenic Specificity | CD273 (B7-DC) |
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| Clone | MIH18 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, kappa |
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| Format | unconjugated, functional grade |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD273 (B7-DC) Monoclonal Antibody (MIH18), Functional Grade, eBioscience™. Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; this a |
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| Immunogen | n/a |
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| Other Names | B7-DC, Btdc, F730015O22Rik, MGC124039, MGC124040, PD-L2 |
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| Gene, Accession # | Entrez: 80380; Uniprot: Q9BQ51 |
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| Catalog # | 16-5888-86 |
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| Price | |
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| Order / More Info | CD273 (B7-DC) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 18791172, 19017976, 19380770, 20123111, 25073001, 26236467, 29409495 |
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