| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD273 (B7-DC) |
|---|
| Clone | MIH18 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1, kappa |
|---|
| Format | phycoerythrin (PE) conjugate |
|---|
| Size | 100 Tests |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 5 µL (0.125 µg)/test |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD273 (B7-DC) Monoclonal Antibody (MIH18), PE, eBioscience™. Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; this antibody is spe |
|---|
| Immunogen | n/a |
|---|
| Other Names | B7-DC, Btdc, F730015O22Rik, MGC124039, MGC124040, PD-L2 |
|---|
| Gene, Accession # | Entrez: 80380; Uniprot: Q9BQ51 |
|---|
| Catalog # | 12-5888-42 |
|---|
| Price | |
|---|
| Order / More Info | CD273 (B7-DC) Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 16598819, 18253710, 19380770, 19936055, 20657553, 21540239, 21795591, 24696476, 25275395, 26155412, 26260996, 27564103, 29409495, 29721192 |
|---|
| 产品资料 |
|
|