| 产品详情 |
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| Antigenic Specificity | CD273 (B7-DC) |
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| Clone | TY25 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, kappa |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5 µg/test, Functional Assay: Assay-Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Immunoprecipitation: Assay-Dependent, Neutralization: Assay-Dependent, Western Blot: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD273 (B7-DC) Monoclonal Antibody (TY25), eBioscience™. Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; this antibody is specific |
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| Immunogen | n/a |
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| Other Names | B7-DC, Btdc, F730015O22Rik, MGC124039, MGC124040, PD-L2 |
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| Gene, Accession # | Entrez: 58205; Uniprot: Q9WUL5 |
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| Catalog # | 14-5986-81 |
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| Price | |
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| Order / More Info | CD273 (B7-DC) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12847137, 16061819, 18719016, 19017976, 20048044, 20574047, 20628373, 21078902, 21195478, 22993390, 24015822, 24677019, 24890099, 25086775, 25157219, 25568183, 26147684, 28130292 |
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