| 产品详情 |
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| Antigenic Specificity | KPNA1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 2.5 µg/mL, Immunofluorescence: 20 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | KPNA1 Polyclonal Antibody. Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA1, also known as importin alpha 5, is the alpha subunit of karyopherin, which forms a complex with importin subunit beta-1 and functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. It is ubiquitously expressed and polyubiquitinated in the presence of RAG1. KPNA1 interacts with various virus nucleop |
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| Immunogen | n/a |
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| Other Names | IPOA5, NPI-1, RCH2, SRP1; RAG cohort protein 2; SRP1-beta; importin alpha 5; importin subunit alpha-1; importin-alpha-S1; karyopherin subunit alpha-1; nucleoprotein interactor 1; recombination activating gene cohort 2 |
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| Gene, Accession # | Entrez: 16646, 288064, 3836; Uniprot: P52294, P83953, Q60960 |
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| Catalog # | PA5-21032 |
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| Price | |
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| Order / More Info | KPNA1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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