| 产品详情 |
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| Product Name | Recombinant Human Guanine nucleotide-binding protein-like 3-like protein (GNL3L) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 81.6kDa. Full Length: 1-582aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | GNL3L, UniProt: Q9NVN8 |
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| Catalog # | RPC23567 |
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| Price | |
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| Order / More Info | Recombinant Human Guanine nucleotide-binding protein-like 3-like protein (GNL3L) from BIOMATIK |
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| Product Specific References | n/a |
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