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| Product Name | Recombinant Human Guanine nucleotide-binding protein subunit alpha-13 (GNA13) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 48.0kDa. Full Length: 1-377aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG). GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1).Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway. Inhibits CDH1-mediated cell adhesion in process independent from Rho activation |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | GNA13, UniProt: Q14344 |
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| Catalog # | RPC25950 |
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| Order / More Info | Recombinant Human Guanine nucleotide-binding protein subunit alpha-13 (GNA13) from BIOMATIK |
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| Product Specific References | n/a |
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